Skip to Menu Skip to Search Contact Us Global Websites & Languages Skip to Content

How and When to Use Multiple Techniques in Biophysical Protein Characterization

The aggregation of biopharmaceuticals is a complex physical process. Its analysis requires the use of a selection of suitable methods to build up a comprehensive dataset that can then support appropriate interpretation and scientifically sound conclusions.

The orthogonal methods discussed in this white paper (SV-AUC, SEC, SEC-MALS, DLS, SDS-Page and FFF) provide ways of characterizing soluble aggregates but have a number of limitations in their abilities to provide quantitative information. Proper method selection ensures data is both orthogonal and valuable, and that none of the data collected is redundant.


Please complete the form to download your copy.

Fields marked with an asterisk (*) are mandatory.

White paper request form

Are you an SGS client?*

200 characters remaining