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A complete range of highly sensitive analyses from SGS, providing you with a detailed understanding of peptide and protein primary structure to GLP/cGMP standards.

Life Science

Primary structural analysis requires a high level of expertise in a variety of disciplines. As a pioneer of physicochemical characterization, we offer you unrivaled expertise in peptide and protein sequence analysis. Our laboratories helped establish some of the key mass spectrometry (MS) methods used today for mapping of biotechnology products, some of which have now become standard approaches worldwide.

Our primary peptide and protein analyses are based around the requirements of ICH guidelines (particularly ICH Q6B), U.S. FDA 'Points to Consider' documents and the concept of a 'well characterized' or 'specified' biological product.

Our individual primary structural analyses, available to GMP and GLP standards, include:

  • Amino acid sequencing by MS
  • N-terminal sequencing by Edman
  • C-terminal sequencing
  • Molecular weight determination
  • De novo sequencing
  • Qualitative and quantitative determination of modifications such as oxidation, deamidation, acetylation, methylation and cross-linking
  • Post-translational modifications

As a world leading provider of testing and analysis for the life sciences industry, our expertise and breadth of capabilities make us your ideal partner in protein and primary peptide analysis.

To discuss your peptide and protein testing requirements, contact us today.