Optimize drug efficacy and safety with our preclinical formulation development platform.
Navigating the early stages of drug development often presents a dilemma. With limited available data on the active pharmaceutical ingredient (API) and small quantities at hand for studies, formulating the right approach for drug delivery can be challenging.
We provide a structured pre-formulation pathway to ensure the efficient screening of lead candidates, maximizing the dose that can be administered and is available for absorption.
Where limited data is available, API characterization services may be employed such as:
Typically to establish the formulation approach, we undertake the following studies:
Approaches to formulation may include:
Prototype development studies may include:
We aim to establish prototype formulations suitable for evaluation in non-clinical PK or toxicological studies, within 6 to10 weeks of receipt of the API, subject to formulation complexity.
