This webinar will provide insights into advanced bioanalytical approaches supporting oligonucleotide analysis, clinical development and biomarker research. Attendees will gain practical insights into the analysis and quantification of complex oligonucleotides, including siRNA quantification using LC-MS/MS and alternative approaches such as LC-Fluorescence, while exploring our end-to-end bioanalytical services, spanning safety testing, PK/PD, biomarkers, method development and validation, sample analysis, reporting and data transfer.
The session will also highlight how next-generation technologies are transforming biomarker discovery and clinical research. Learn how the Olink Signature Q100 platform enables highly sensitive, multiplex protein analysis from minimal sample volumes, supporting biomarker research and more informed decision-making throughout the drug development process.
Agenda
- Introduction to oligonucleotides and key analytical considerations
- Navigating complex oligonucleotide analysis using LC-MS/MS
- Case study: siRNA quantification and LC-Fluorescence as an alternative analytical approach
- Exploring SGS's integrated bioanalytical capabilities across clinical development
- Leveraging the Olink Signature Q100
- Q&A
Target Audience:
The webinar is intended for professionals involved in oligonucleotide therapeutics, siRNA research, biomarker development and clinical research. Whether you work in bioanalysis, analytical or method development, translational medicine, PK/PD, proteomics, biomarker discovery, drug development or the broader biotechnology and pharmaceutical sectors, the session will provide practical insights into advanced bioanalytical strategies and technologies supporting modern drug development.
Language: English
Can't make a live session? Register now and receive a complimentary recording after the live event. For further information, please contact us.
Speakers:
Alicia König
Molecular Biologist
Alicia joined SGS in September 2022 and currently holds the position of Molecular Biologist (M.Sc.) in Berlin, Germany. She supports a broad range of molecular testing and analytical activities for pharmaceutical and biotechnology clients. Working as part of SGS's Health & Nutrition team, Alicia contributes to high-quality laboratory services that help clients at every stage of their drug development journey, from early development through to regulatory and commercial support.
Wassim Kaaki
Head of LC/MS Unit
Wassim joined SGS in August 2017, first working as LC/MS Study Director before taking the position of Laboratory Head in January 2021. Alongside the day-to-day administration of the laboratory, he also supports the development of short-and long-term projects for clients across the biopharmaceutical sector.