You are accessing SGS's website from the USA.

Would you like to visit the US website?

Share on LinkedInShare on LinkedInShare on FacebookShare on FacebookTweet thisTweet this

Life Sciences


Minimize menuMaximize menu

Minimize menuMaximize menuHomeLife SciencesPharmaceutical ServicesClinical Research ServicesClinical PharmacologyClinical Pharmacokinetics & Pharmacodynamics

Related Links

Clinical Pharmacokinetics and Pharmacodynamics

As a world leader in clinical trials, SGS provides you with extensive clinical pharmacokinetics services and analysis (PK) and pharmacodynamic (PD) support in pre-clinical and Phase I to III clinical studies.

We offer high-quality procedures and results complying with international regulatory standards (FDA, EMEA, ICH), in Phase I facilities in the EU (in Antwerp, totaling 92 beds). 

Clinical Expertise

  • Pre-clinical PK and toxicokinetics (GLP compliant)
  • Bioequivalence and comparative bioavailability
  • ADME pharmacokinetic services (C14 studies)
  • Modified release formulations
  • Transdermal drug delivery
  • Inhaled drugs
  • Immunological response
  • PD profiling of pharmacological effects, including a large range of biomarkers

Pharmacokinetic and Pharmacodynamic Analysis

Our pharmacokineticists each have, on average, over 10 years’ experience, and support our clients with:

  • Expert PK input to preclinical and clinical development plans
  • Evaluation of safety data and animal tissue distribution data
  • Study design: sample size calculation, optimized sampling schedule
  • Non-compartmental and compartmental analysis
  • PK/PD Modeling and simulation (including population approach)
  • Pooled analysis
  • Statistical analysis and reporting of PK and PD outcomes
  • Preparation of scientific publications and investigator brochures
  • Experience with all kind of study designs and data analysis, like, first-in-human, DDI, BA/BE, PK, POC, ADME (C14) and PK in special populations

Software tools

  • WinNonlin®
  • NonNem®
  • Sigmaplot facilities, for macro creation and statistical reporting.

Contact SGS today to learn how we can help with your clinical pharmacokinetics and pharmacodynamics testing.

Email us
Exploratory DevelopmentExploratory Development to Proof of Concept Integrated services reduce time to market (PDF 876KB) ...
14C ADME Clinical TrialsWhy, When, and How to Conduct 14C Human StudiesFactors in conducting a radiolabeled ADME study (PDF 185KB) ...
Interactive Pocket MapLife Science Services Interactive Pocket MapA quick reference to our global sites and services. ...
PharmacodynamicClinical Trial ModelsPharmacodynamic ModelsAn overview of the PD model techniques offered by SGS ...


SGS Headquarters

  • 1 Place des Alpes
    P.O. Box 2152
    1211 Geneva 1
  • t   +41 22 739 91 11
  • f   +41 22 739 98 86
  • e   Email us


Sign up to SGS publications and newsletters from your region and around the world.

Office Directory

Find SGS offices and labs around the world.World map
Office Locator